GO:0070268 biological_process cornification
| PAG Title | GO:0070268 biological_process cornification |
| PAG ID | TAX028836 |
| Type | A |
| Source Link |  GOA |
| Publication Reference | NA |
| PAG Description | A type of programmed cell death that occurs in the epidermis, morphologically and biochemically distinct from apoptosis. It leads to the formation of corneocytes, i.e. dead keratinocytes containing an amalgam of specific proteins (e.g., keratin, loricrin, SPR and involucrin) and lipids (e.g., fatty acids and ceramides), which are necessary for the function of the cornified skin layer (mechanical resistance, elasticity, water repellence and structural stability). |
| Species | Homo sapiens |
| nCoCo Score | 380 |
| Base PAG ID | TAX028836 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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